08168958821
Home » Pharmaceutical Sciences » ESTIMATION OF THE EFFECT OF CISAMPELOUS OWANRENSIS BENZENE FRACTION ON GLUCOSE A...
ESTIMATION OF THE EFFECT OF CISAMPELOUS OWANRENSIS BENZENE FRACTION ON GLUCOSE ABSORPTION ACROSS THE INTESTINAL EPITHELIUM OF WISTER RATS ON ALOXAN INDUCED DIABETES
Sold By: Joe Project Store | Item Type: Project Material | Report this? | Attributes: 50 pages | 1-5 chapters | Amount: ₦5,000 | Marked useful: 6,096 times
Delivery: Within 24 hoursABSTRACT
Diabetes is a global public health crisis that threatens the economies of all nations, particularly developing countries. It is generally characterized by hyperglycaemia and hyperlipidaemia culminating in severe morbidities. This study aimed to assess the effects of Cissampelos owanrensis on glucose absorption in alloxan-induced diabetic male Wistar rats. Twenty (20) adult. Wistar rats were divided into four (4) groups of five rats each (n=5). Groups 1 and 2 served as the control groups and group 3 and 4 were induced with diabetes by an intraperitoneal injection of alloxan (40mg/kg). The normoglycaemic groups (1 and 2) and the alloxan-induced diabetic groups (3 and 4) were treated with 300mg/kg of Cissampelos owanrensis. The fasting glucose level of the animals was monitored at 1 hour, 3 hours and 4 hours. At the end of the experiment the rats were sacrificed by cervical dislocation, blood samples were centrifuged to obtain the serum for biochemical analysis. The duodenum, jejunum and ileum were excised for biochemical study. Data obtained were analyzed using SPSS statistical tool and expressed as mean±SEM. Results show that fasting blood glucose levels of diabetic rats was reduced significantly on administration of 300mg/kg of the plant extract(502.33±5.57 after 1 hour, 427.33±7.67 after 3 hours, 298.33±10.91 after 4 hours). In conclusion, benzene fractions of Cissampelos owanrensis demonstrated significant reduction in glucose absorption across the intestinal epithelium.
This material content is developed to serve as a GUIDE for students to conduct academic research
Delivery: Within 24 hours
Advertise Here
Not what you were looking for? Perform a search
What's your project topic?
Comment on Facebook:
Related Project Materials
- 1.
ISOLATION OF MICROORGANISM ASSOCIATED WITH DETERIORATION OF BANANAS FRUITS
CHAPTER ONE INTRODUCTION Banana is a long curved fruit which grows in clusters and has soft pulpy flesh and yellow skin when ripe.There are about 1000...More »
Item Type: Project Material | 50 pages | 10,045 engagements |
- 2.
PHARMACOECONOMIC ANALYSIS OF HIV/AIDS MANAGEMENT PHARMACY
ABSTRACT The HIV/AIDS pandemic has resulted in mortality surge and life expectancy drop throughout the world. Developing countries are mostly affected...More »
Item Type: Project Material | 50 pages | 9,560 engagements |
- 3.
DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PUR...
ABSTRACT Two simple, sensitive, accurate and extraction free spectrophotometric methods were developed and described for the determination of risperid...More »
Item Type: Project Material | 50 pages | 8,278 engagements |
- 4.
WORKING CAPITAL MANAGEMENT AND PROFITABILITY OF LISTED PHARMACEUTICAL FIRMS IN NIGERIA
ABSTRACT Working capital managemt involves the management of the most liquid resources of the firm which includes cash and cash equivalents, inventori...More »
Item Type: Project Material | 50 pages | 7,144 engagements |
- 5.
INVESTIGATING THE PRESENCE OF STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI IN DAIRY PRODUCTS
CHAPTER ONE INTRODUCTION1.1 BACKGROUND OF THE STUDY Dairy products are various products derived from cow’s milk or that of other female mammals ...More »
Item Type: Project Material | 50 pages | 9,412 engagements |
- 6.
RECYCLING WASTE POLYETHYLENE MATERIALS TO USEFUL PRODUCTS VIA PYROLYSIS
Chapter oneIntroduction1.1 Background of study Recycling is a process of changing waste materials into new products to prevent waste of potential...More »
Item Type: Project Material | 50 pages | 8,856 engagements |